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Dr. Leanne Holt discusses astrocytic CREB's role in addiction-related behaviors. Using advanced imaging and AI analysis, her research highlights transcriptional changes influencing microglia morphology in the nucleus accumbens, central to addiction vulnerability.

Astrocyte Signaling & Addiction: Linking CREB to Glial Function

Key Takeaways

  • Research focus: CREB's influence on astrocyte and microglia interactions.
  • Model system: Mouse models exploring nucleus accumbens in addiction.
  • Research goal: Understand astrocyte's transcriptional regulation affecting behavior.
  • Presented by: Dr. Leanne Holt, postdoctoral fellow at Mount Sinai.
  • Content type: Educational Webinar on gliobiology and addiction.
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Webinar: Astrocytes, Microglia, and Addiction by Dr. Leanne Holt

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